Filaggrin

Example:The expression of kinetic filaggrin is increased in the skin of individuals with eczema.

Definition:A variant of filaggrin that is involved in the skin's mechanical strength and resistance.

Example:Mutated filaggrin is often found in individuals with atopic dermatitis, contributing to skin dryness and irritation.

Definition:A form of filaggrin that is altered due to genetic mutations, leading to skin barrier deficiencies.

Example:Researchers use murine filaggrin to model human skin conditions in their experiments.

Definition:The filaggrin protein found in mice, often studied in genetic research to understand human skin diseases.

Example:Human filaggrin was identified as a key gene in the genetics of atopic dermatitis.

Definition:The filaggrin protein found in humans, crucial for skin health and barrier function.